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Kronisk smerte er altså en smertetilstand som har vart mer enn three måneder5. I denne sammenhengen betyr ikke ordet kronisk at du aldri blir kvitt smerten, bare at den har vart lenge. Vi kunne like gjerne kalt det langvarig smerte.Det er blitt funnet at høye doser av medikamentet kan forårsake irreversible endringer i leveren og fremme leversv